It's been a good, long run. After Season 10 closes, Sandra Oh will be exiting Grey's Anatomy, the hit ABC medical drama she's been a star of since its premiere in 2005. The Hollywood Reporter reports that Oh, who plays doctor Chirstina Yang, will begin focusing on other opporunties. "Creatively, I really feel like I gave it my all, and I feel ready to let her go," she said. Oh spilled the news to her costars at a table reading for the show's 200th episode Tuesday. "For the first time, at least for my character, you actually have an endpoint, which in series television you never or very rarely have. Letting go of such a huge part of my life … I want to cry right now."