Michael Douglas is opening up about his recent rounds of chemo and radiation to treat the cancerous tumor at the base of his tongue. "It really knocks you out," he told People magazine in a new cover story. After contending with persistent throat and ear pain the Oscar-winning actor was given stage 4 throat cancer prognosis in August. "The hardest part is seeing his fatigue, because Michael is never tired," said his wife, Catherine Zeta-Jones, who, despite the road ahead, remains optimistic. "If there's anything Michael has, it's strength."