A powerful blast ripped across a Shia-majority area in Karachi, Pakistan, killing at least 45 people and injured 150 during evening prayers Sunday. The bomb, which exploded near a mosque as worshippers left evening prayers, destroyed several buildings and caused a power cut in the area. Residents and rescue workers have been struggling to search for survivors trapped in the rubble as night falls. "I saw people burning to death and crying with pain. I saw children lying in pools of their own blood and women running around shouting for their children and loved ones," a resident told Reuters. No group has claimed responsibility for the explosion.